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To prepare and submit 10 ml of calamine lotion.

 Experiment

Prepration of calamine lotion b.pharm 1st sem


    AIM:

     To prepare and submit 10 ml of calamine lotion.

    Apparatus: 

    Mortar pestle, beaker (250 ml), measuring cylinder (10 ml. 50 ml), Spatula and glass rod.

    Materials/formula:

    Rx
    Calamine 8 g.
    Zinc oxide 8 g.
    Glycerin 6 ml.
    Lime water to 100 ml.

    Fiat: lotion (to make lotions)
    Mitte: 10 ml
    Sig. M.D.U. (More Dicto Utendus) ( to be used as directed)

    Theory:

    Lotions are dilute aqueous solutions or suspensions meant for external application to the body. They may 
    be applied to the skin, hair or eyes. They are applied without friction. 
    They may contain:
    Humectants ; to retain moisture on the skin after
     application
    Alcohol ; which evaporates quickly causes a cooling
     effect and leaving the skin dry.

    Procedure:

    1. Mix calamine and zinc oxide together in a mortar till a homogenous 
     powder is obtained.
    2. Pour glycerin and triturate to form a homogeneous paste.
    3. Add a small portion of lime water and continue trituration till a 
     very smooth levigate is obtained.
    4. Dilute the smooth levigate with small portion of calcium hydroxide solution (lime water), then
    with large portion following by trituration after each addition till attaining the final 
     volume. 

    Uses: 

    Soothing and protective in cases of skin irritation and dermatitis.

    Lime water: Saturated calcium hydroxide solution (1.5g/L at 25ºC sparsely soluble).

    Storage: 

    • Store below 30℃.
    • Do not freeze.
    • Keep away from direct sunlight.
    Direction for use:
     Apply a thin layer 

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